We're in constant pursuit of breakthroughs that change patients' lives. We innovate daily to make the world a healthier place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more creative, recruit and maintain the best talent, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—drives everything we do and shows our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and represents the value we work to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We fulfill our purpose by seeking the best science in the world, working with others in the healthcare system to increase access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.