We are in relentless pursuit of breakthroughs that transform patients' lives. We create innovations every day to make the world a better place. This was Charles Pfizer's initial vision, and it still holds true today. Research confirms what we instinctively know: that purpose-driven companies deliver better results, are more inventive, attract and retain the best talent, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and reflects our passion for growing our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and embodies the value we work to bring to patients and society. Our purpose ensures that patients remain at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to increase access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.