We are in constant pursuit of breakthroughs that change patients' lives. We drive innovation every day to make the world a more healthy place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what we instinctively know: that purpose-driven companies deliver better results, are more innovative, draw and keep the best people, and know how to harness the power of those people. Pfizer's purpose—Breakthroughs that transform patients' lives—drives everything we do and shows our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has significance and reflects the value we strive to bring to patients and society. Our purpose guarantees that patients stay at the centre of all we do. We embody our purpose by sourcing the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, using digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can prosper.